All four group winners were defeated by runners-up on a surprising day of men's quarter-final action at the International University Sports Federation University World Cup Football in Jinjiang.
The casualties in China included Brazil's Paulista University, who many considered the pre-tournament favourites.
They were held to a 1-1 draw by the Autonomous University of Mexico State, who then triumphed 3-2 via a penalty shoot-out.
In an all-Asian quarter-final, Thailand's Bangkok Thonburi University fell to South Korea's Myongji University, also after spot kicks.
The Koreans came through 5-3 after a goalless draw.
Spain's University of Malaga were unbeaten in the group stage but fell to Uruguay's University of the Republic who registered a 2-0 victory.
Australia's University of Wollongong also won 2-0 to eliminate Russia's Smolensk State Academy of Physical Education.
In the semi-finals on Friday (November 29), Autonomous University of Mexico State take on the University of Wollongong, with the University of the Republic meeting Myongji University.
The women's semi-finals are tomorrow.