Home interest was ended at the Badminton World Federation Spain Masters as Beatriz Corrales was knocked out of the women's tournament in Barcelona.
The eighth-seed was beaten 21-17, 21-15 by Japan's Minatsu Mitani on quarter finals day at the Pavelló de la Vall d'Hebron.
Spain were hoping for success at the event as Carolina Marin, the Rio 2016 Olympic gold medallist who won her third world title this month, was initially the top seed.
However, her withdrawal on the eve of the tournament left home hopes with Corrales.
Mitani will now play Scotland's Kirsty Gilmour who knocked out Japan's second seed Sayaka Takahashi, 21-16, 11-21, 21-15.
The other semi-final will be an all-Danish affair.
Third-seed Mia Blichfeldt made it through by beating Thailand's Busanan Ongbamrungphan 21-18, 21-17.
Line Kjærsfeldt, the seventh seed, knocked out Germany's Yvonne Li 21-17, 21-18.
In the men's draw, Thailand's top seed Suppanyu Avihingsanon marched on.
He booked his place in the last four with a 21-16, 21-14 win over Israel's seventh seed Misha Zilberman.
His next opponent will be Japan's Yu Igarashi, the fifth seed who knocked out the fourth seed in Denmark's Jan Ø. Jørgensen, 21-10, 21-13.
Second-seeded Dane Rasmus Genke met India's Ajay Jayaram and came through 13-21, 21-13, 21-11.
He will play England's Toby Penty, a 21-12, 21-11 winner over Denmark's Victor Svendsen.
The semi-finals at the Super 300 event will be held tomorrow.