Findings published in the World Anti-Doping Agency (WADA) Report will be taken "extremely seriously" by the International Paralympic Committee (IPC), who have pledged to study it in "great detail" to ascertain if results at Sochi 2014 were affected.
They vowed to "act accordingly" if any evidence of doping is found.
Undertaken by a three-man Independent Commission chaired by founding WADA President, Richard Pound, the Report dealt specifically with allegations of systemic doping within Russian athletics.
Its findings, however, included the allegation that Russia's FSB secret police interfered in anti-doping activity at the Sochi laboratory used during last year's Winter Olympics and Paralympics, potentially casting doubt on the medal-table topping performances of the home nation's athletes at both Games.
"Its impartiality, judgment and integrity were compromised by the surveillance of the FSB within the laboratory during the Sochi Winter Olympic Games," the teport claimed.
"The reported presence of the security services [FSB] within the laboratory setting in Sochi and at the Moscow laboratory, actively imposed an
atmosphere of intimidation on laboratory process and staff, and supported allegations of state influence in sports events."
Russia won 30 Paralympic golds, 28 silvers and 22 bronze at Sochi 2014 to finish with a total haul of 80 medals, 65 more than any other country.
This was a huge increase of their performances at previous Winter Paralympics.
A total of 24 of the gold medals coming in biathlon and cross-country skiing, endurance sports which Pound claimed yesterday have "a lot of doping problems, and not just from Russians".
“The IPC takes the findings of the WADA report extremely seriously," the body's communications director Craig Spence told insidethegames today.
"Over the coming days we will study the report in great detail with regard to what impact it could have on the Paralympic Movement and the Paralympic Games.
“The IPC is committed to protecting clean athletes and ensuring clean sport for all.
"If the IPC believes any anti-doping rule infringements have taken place then we will act accordingly.”
Pound said yesterday that he does not "think we can be confident there was no manipulation of results at Sochi 2014.
"We have no concrete proof, but it's hard to imagine what the Russian state interest would be in urine samples otherwise."
The Paralympics, held in March, took place under a cloud of controversy, opening just days after Russian troops invaded the Crimean Peninsular, which then belonged to Ukraine.
Russian President Vladimir Putin repeatedly praised the IPC and its President Sir Philip Craven for supporting sport over politics during the Games.
November 2015: Russian Sports Ministry urges WADA to focus "on real facts and evidence" as fails to deal with key findings of damning report
November 2015: Russia given until end of week by Coe to respond to WADA report
November 2015: WADA Report accuses Russian secret police of "direct intimidation and interference" in promoting systemic doping
December 2014: Sochi 2014 named International Paralympic Committee's top moment of the year
March 2014: Putin thanks IPC for supporting sport over politics at Sochi 2014